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Inhibitory Effects of Proanthocyanidin-rich Extract from Grape Seeds on Melanogenesis … Shizuka UEHARA, Yuki MIZUTANI, Masato NAKADE, Osamu SAKATA, Ichiro SASAKI, Kumi ARAKANE, Tadashi SUZUKI, Riichiro UCHIDA, Shoichi TOKUTAKE … 247
Key words: melanin, tyrosinase, melanogenesis, proanthocyanidin, MALDI-TOF MS.
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Involvement of Melanin Monomers in the Skin Persistent UVA-Pigmentation and Effectiveness of Vitamin C Ethyl on UVA-Pigmentation … Kazuhisa MAEDA, Yoshihiko INOUE, Hiroshi NISHIKAWA, Satoko MIKI, Osamu URUSHIBATA, Tokutaro MIKI, Masato HATAO … 257
Key words: ethyl ascorbic acid, DHICA, 6H5 MICA, melanin, UVA.
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Symposium
Etiological Aspects and Prevention of Lentigo Senilis … Masako MIZOGUCHI … 269
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Suppression of Melanogenesis by Induction of Endogenous Intracellular Antioxidant in Human Melanocytes … Minoru SASAKI … 271
Key words: metallothionein, intracellular antioxidant, tyrosinase, melanogenesis.
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Whitening Effects of Antioxidants … Yasunobu OCHIAI, Yuri OKANO, Hitoshi MASAKI … 275
Key words: vitamin E, glutathione, melanocyte, keratinocyte, ultraviolet.
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The Suppression of Melanosome Transfer and Its Evaluation … Tomohiro HAKOZAKI … 280
Key words: melanosome transfer, hyperpigmentation, skin-lightening, niacinamide.
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Strategy for Developing Anti-Wrinkle Agents― Mechanisms of aging and photoaging and their prevention― … Masamitsu ICHIHASHI … 285
Key words: UV, photoaging, aging, wrinkle, DNA damage, ROS, MMP.
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Wrinkle Care by Improving Skin Elastic Properties … Yoshinori TAKEMA … 290
Key words: wrinkle, elastic property, evidence, efficacy evaluation.
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Collagen Fiber Bundles and Wrinkling … Yasutomo NISHIMORI … 294
Key words: wrinkle, collagen, ursolic acid.
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Effect of Antioxidant to Inhibit UV-Induced Wrinkles … Kumi ARAKANE … 298
Key words: antioxidative effect, antioxidant, wrinkle, photoaging, reactive oxygen species.
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Technical Information … 304
Book Review … 319
Report … 320
Contents to Vol. 27 … 322
Announcement … 329