Journals Vol.47 No.1

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Regular Articles

Skin Sensitization Potency Prediction of Ingredients in Hair Colorants Using in silico Models of Machine Learning … Takao ASHIKAGA, Kazuto NARITA, Mutsumi KOBAYASHI, Shigehiro TACHIBANA, Wataru MURASAKI, Masaharu SUZUKI, Kaori AMBE, Masahiro TOHKIN … 1
Key words: skin sensitization, potency prediction, alternatives, machine learning, hair dye.
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Involvement of Increased Numbers of Dysfunctional Mitochondria and the Accumulation of Fe2+ in the Enhanced Generation of ROS in Replicative Senescent Human Epidermal Keratinocytes … Nene SHIMODA, Ayumi HIRAMATSU, Yoshinobu TSURUTA, Kaede AKASHIKA, Moemi YOSHIDA, Satoshi TOSHIMOTO, Mikako YAGI, Yuichi MATSUSHIMA, Masayuki YAGI, Masamitsu ICHIHASHI, Hideya ANDO … 6
Key words: ROS, replicative senescence, keratinocyte, mitochondria, hydrogen peroxide.
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Seminars

Age-Related Wrinkle and Sagging; The Mechanism and How to Treat … Nariaki MIYATA … 15
Key words: wrinkle, sagging, energy-based device, injectable, thread.
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Cosmetics R&D Targeting Sagging … Tomonobu EZURE … 16
Key words: sagging, wrinkle, subcutaneous adipose layer, mimetic muscle, beauty method.
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Basic Lecture

Allergic Contact Dermatitis Due to Hair Products … Akiko ITO … 22
Key words: allergic contact dermatitis, patch test, hair products, p-phenylenediamine, methylisothiazoline.
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Skin Disorders Due to Skin Care Products/Face Cleansers … Mariko SUGIURA, Keiji SUGIURA … 28
Key words: contact dermatitis, skin care product, cleanser, patch testing, Japanese baseline series.
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Topic

Tokuro IWABUCHI … 34
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Technical Information … 37
Reports on Related Research Meetings … 79
Notice on Related Research Meetings … 82
Announcement … 85